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No evidence for allelic association between bipolar disorder and monoamine oxidase a gene polymorphisms

✍ Scribed by Craddock, Nick ;Daniels, Johanna ;Roberts, Enriqueta ;Rees, Mark ;McGuffin, Peter ;Owen, Michael J.

Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
370 KB
Volume
60
Category
Article
ISSN
0148-7299

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✦ Synopsis

~ W e have tested the hypothesis that DNA markers in the MAOA gene show allelic association with bipolar affective disorder. Eighty-four unrelated Caucasian patients with DSM 111-R bipolar disorder and 84 Caucasian controls were typed for three markers in MAOA a dinucleotide repeat in intron 2, a VNTR in intron 1, and an Fnu4HI RFLP in exon 8. No evidence for allelic association was observed between any of the markers and bipolar disorder. @

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