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No association of tumor necrosis factor alpha gene polymorphisms with schizophrenia or response to clozapine

✍ Scribed by Shih-Jen Tsai; Chen-Jee Hong; Younger W.-Y. Yu; Ching-Hua Lin; Ling-Ling Liu


Book ID
119555059
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
105 KB
Volume
65
Category
Article
ISSN
0920-9964

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The striking evidence of almost 100% association of narcolepsy with human leukocyte antigens (HLA) DR2(DR15) antigen is an important clue to elucidate the molecular basis of this sleep disorder. The gene for tumor necrosis factor ␣ (TNF ␣) is located in the HLA class II gene cluster. Recent studies