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No association between the G308A polymorphism of the tumor necrosis factor-alpha gene and schizophrenia

✍ Scribed by Michael Riedel; Holger Krönig; Markus J. Schwarz; Rolf R. Engel; Kai-Uwe Kühn; Christopher Sikorski; Safet Sokullu; Manfred Ackenheil; Hans-Jürgen Möller; Norbert Müller


Publisher
Springer-Verlag
Year
2002
Tongue
English
Weight
161 KB
Volume
252
Category
Article
ISSN
1433-8491

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The striking evidence of almost 100% association of narcolepsy with human leukocyte antigens (HLA) DR2(DR15) antigen is an important clue to elucidate the molecular basis of this sleep disorder. The gene for tumor necrosis factor ␣ (TNF ␣) is located in the HLA class II gene cluster. Recent studies