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No association between the tumor necrosis factor-alpha gene promoter polymorphisms and schizophrenia in a Japanese population

✍ Scribed by Yuichiro Watanabe; Tatsuyuki Muratake; Naoshi Kaneko; Naoki Fukui; Yasushi Nara; Toshiyuki Someya


Book ID
116849111
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
146 KB
Volume
153
Category
Article
ISSN
0165-1781

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The striking evidence of almost 100% association of narcolepsy with human leukocyte antigens (HLA) DR2(DR15) antigen is an important clue to elucidate the molecular basis of this sleep disorder. The gene for tumor necrosis factor ␣ (TNF ␣) is located in the HLA class II gene cluster. Recent studies