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No association detected between a D3 receptor gene-expressed variant and schizophrenia

✍ Scribed by Rothschild, Leelach G.; Badner, Judith; Cravchik, Anibal; Gershon, Elliot S.; Gejman, Pablo V.


Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
11 KB
Volume
67
Category
Article
ISSN
0148-7299
DOI
10.1002/(sici)1096-8628(19960409)67:2<232::aid-ajmg18>3.0.co;2-k

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✦ Synopsis


A missense polymorphism (glycine to serine) in the first exon of the dopamine D3 (DRD3) gene was examined in a sib-pairs schizophrenia collection by the transmission test for linkage disequilibrium (TDT).

No association due to linkage disequilibrium was detected using TDT. Additionally, no evidence for excess homozygosity was found.


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