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No association between α1-antichymotrypsin polymorphism, apolipoprotein E and patients with late-onset Alzheimer's disease

✍ Scribed by Seppo Helisalmi; Arto Mannermaa; Maarit Lehtovirta; Markku Ryynänen; Paavo Riekkinen Sr.; Hilkka Soininen

Book ID: 117475618
Publisher: Elsevier Science
Year: 1997
Tongue: English
Weight: 60 KB
Volume: 231
Category: Article
ISSN: 0304-3940
DOI: 10.1016/s0304-3940(97)00525-9

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To examine the possible involvement of the alpha-1-antichymotrypsin gene (ACT) polymorphism in the manifestation of Alzheimer's disease (AD), we analyzed genotypes of the ACT and apolipoprotein E gene (APOE) among 110 Korean patients with probable AD and 209 nondemented controls. No significant diff