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No association between the androgen receptor gene CAG repeat and impaired sperm production in Swedish men


Book ID
110887839
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
157 KB
Volume
54
Category
Article
ISSN
0009-9163

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The human androgen receptor (AR) gene possesses 2 trinucleotide repeats of CAG and GGN in exon 1. The CAG repeat corresponds to a polyglutamine tract in the N-terminal region of the receptor, that affects its transcriptional efficiency. The GGN repeat codifies for a polyglycine tract, and affects th