Linkage disequilibrium between the androgen receptor gene CAG and GGC repeats in the African-American population
โ Scribed by Scott M. Gilbert; Mitchell C. Benson; James M. McKiernan
- Book ID
- 107554674
- Publisher
- Springer
- Year
- 2002
- Tongue
- English
- Weight
- 211 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1527-2737
No coin nor oath required. For personal study only.
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The human androgen receptor (AR) gene possesses 2 trinucleotide repeats of CAG and GGN in exon 1. The CAG repeat corresponds to a polyglutamine tract in the N-terminal region of the receptor, that affects its transcriptional efficiency. The GGN repeat codifies for a polyglycine tract, and affects th