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(CAG)nCAA and GGN repeats in the human androgen receptor gene are not associated with prostate cancer in a French–German population

✍ Scribed by Correa-Cerro, Lina; Wöhr, Gudrun; Häussler, Jürgen; Berthon, Philippe; Drelon, Eric; Mangin, Philippe; Fournier, Georges; Cussenot, Oliver; Kraus, Petra; Just, Walter

Book ID
110024805
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
86 KB
Volume
7
Category
Article
ISSN
1018-4813

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The human androgen receptor (AR) gene possesses 2 trinucleotide repeats of CAG and GGN in exon 1. The CAG repeat corresponds to a polyglutamine tract in the N-terminal region of the receptor, that affects its transcriptional efficiency. The GGN repeat codifies for a polyglycine tract, and affects th