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NMR spectroscopy in pharmaceutical analysis. VII. Determination of the component composition of gentamicin by13C NMR spectroscopy

โœ Scribed by A. I. Chernyshev; V. S. Kartashov; A. P. Arzamastsev


Book ID
112407496
Publisher
Springer
Year
1991
Tongue
English
Weight
425 KB
Volume
25
Category
Article
ISSN
0091-150X

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Oxazolidine derivatives of p-amino alcohols such as ephedrine have been resolved by -C NMR spedroscopy using Eu(hfc), as a chiral shift reagent. The method is quantitative in the determination of enantiomeric excess, and is advantageous where 'H NMR is of limited use owing, for example, to signitica