NMR spectroscopic study of the inclusion complex of desloratadine with β-cyclodextrin in solution
✍ Scribed by Syed Mashhood Ali; Santosh Kumar Upadhyay; Arti Maheshwari
- Publisher
- Springer Netherlands
- Year
- 2007
- Tongue
- English
- Weight
- 246 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0923-0750
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## Abstract ^1^H NMR spectroscopic study of midazolam hydrochloride (MDL), β‐cyclodextrin (β‐CD) and their mixtures confirmed the formation of β‐CD‐MDL inclusion complex in aqueous solution. The stoichiometry of the complexes was determined by Scott's method to be 1:1, and the association constant
The inclusion complex formation of alpha-cyclodextrin (alpha-CyD), beta-cyclodextrin (beta-CyD), and 2-hydroxylpropyl-beta-cyclodextrin (HP-beta-CyD) with an angiotensin converting enzyme inhibitor, captopril, in aqueous solution was studied by (1)H- and (13)C-nuclear magnetic resonance spectroscopi