NMR spectra of quinidine (I), hydroquinidine (II), and their respective acetyl derivatives (III and IV) were compared. The chemical shifts of some protons in I differed from those of their counterparts in II. These values were concentration dependent in I and II; they were similar in III and IV but
NMR quantitative analysis of quinidine in mixtures of quinidine and hydroquinidine
β Scribed by Tho Huynh-Ngoc; Gerard Sirois
- Publisher
- John Wiley and Sons
- Year
- 1973
- Tongue
- English
- Weight
- 267 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0022-3549
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Complexes of phenobarbital with quinine, quinidine, or hydroquinidine have been prepared and characterized. By means of infrared spectroscopy, these complexes were differentiated from physical mixtures of their respective components when the drug was examined either alone or in harmaceutical dosage
## Abstract A relaxation method was applied to quinidine (1) where crossβrelaxations (Ο~ij~) were obtained by ^1^H selective and biselective __T__~1~ measurements and correlation times for molecular reorientation (Ο~c~) were evaluated from the frequency dependence of the nonβselective __T__~1.~ The