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NMR evidence for self-association of theophylline in aqueous solution: A response

โœ Scribed by David Guttman; Takeru Higuchi


Publisher
John Wiley and Sons
Year
1971
Tongue
English
Weight
199 KB
Volume
60
Category
Article
ISSN
0022-3549

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๐Ÿ“œ SIMILAR VOLUMES


1H and 13C NMR studies of the self-assoc
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## Abstract The ^1^H NMR spectrum of chlorpromazine hydrochloride was fully assigned at 400 MHz. Similarly, the ^13^C NMR spectrum was assigned unambiguously using twoโ€dimensional NMR. Measurements of chemical shift as a function of concentration in D~2~O showed appreciable changes of shift of both

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The interaction of caffeine and theophylline with sodium benzoate and sodium salicylate has been studied in deuterium oxide at 35ยฐC by measnring the aromatic salt-induced changes in the chemical shifts of the N-methyl protons. Taking into account the self-association of the N-methylxanthines, on the

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## Abstract The selfโ€association of pyrimidine and its methylated derivatives was studied by measuring the concentrationโ€dependent changes in proton chemical shifts in deuterium oxide at 35ยฐC. The data were analysed by a dimer model with two parameters. The equilibrium constants give an increasing