## Abstract Formation of complexes between crown ethers and cyclodextrins has been studied using diffusion measurements. The structures of the complexes have been proposed on the basis of the theoretical calculations and the results obtained. Relation between the structural parameters (rings' diame
NMR diffusion coefficient study of steroid–cyclodextrin inclusion complexes
✍ Scribed by Kenneth S. Cameron; Lee Fielding
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 102 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0749-1581
- DOI
- 10.1002/mrc.1083
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✦ Synopsis
Abstract
The complexes formed by the steroid rocuronium bromide with four different cyclodextrins (β‐cyclodextrin, γ‐cyclodextrin, Org 26054 and Org 25969) were investigated. The diffusion coefficients of the steroid–cyclodextrin complexes were 6–15% lower than those of the native cyclodextrins, consistent with a 1 : 1 stoichiometry for all of the complexes. Copyright © 2002 John Wiley & Sons, Ltd.
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## Abstract The host–guest complex formed in aqueous solution between γ‐cyclodextrin (γ‐CD) and the macrocyclic paramagnetic shift reagent TmDOTP^5−^ was examined by NMR spectroscopy. Paramagnetic lanthanide‐induced shifts (LIS) and spin‐lattice relaxation rate enhancements in the proton resonances