NMR Spectroscopic and Molecular Modelling Studies on Cyclodextrin–Dipeptide Inclusion Complexes
✍ Scribed by Claudia Kahle; Ralph Deubner; Curd Schollmayer; Josef Scheiber; Knut Baumann; Ulrike Holzgrabe
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 297 KB
- Volume
- 2005
- Category
- Article
- ISSN
- 1434-193X
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The inclusion complex formation of alpha-cyclodextrin (alpha-CyD), beta-cyclodextrin (beta-CyD), and 2-hydroxylpropyl-beta-cyclodextrin (HP-beta-CyD) with an angiotensin converting enzyme inhibitor, captopril, in aqueous solution was studied by (1)H- and (13)C-nuclear magnetic resonance spectroscopi
## Abstract The host–guest complex formed in aqueous solution between γ‐cyclodextrin (γ‐CD) and the macrocyclic paramagnetic shift reagent TmDOTP^5−^ was examined by NMR spectroscopy. Paramagnetic lanthanide‐induced shifts (LIS) and spin‐lattice relaxation rate enhancements in the proton resonances