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NKG2D regulates production of soluble TRAIL by ex vivo expanded human γδ T cells

✍ Scribed by Dokouhaki, Pouneh; Schuh, Nicholas W.; Joe, Betty; Allen, Christopher A. D.; Der, Sandy D.; Tsao, Ming-Sound; Zhang, Li


Book ID
124064991
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
279 KB
Volume
43
Category
Article
ISSN
0014-2980

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## Abstract Nitrogen containing‐bisphosphonates (N‐BPs), widely used to treat bone diseases, have direct antitumor effects __via__ the inactivation of Ras proteins. In addition to the direct antitumor activities, N‐BPs expand gdγδT cells, which exhibit major histocompatibility complex‐unrestricted