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Adoptive immunotherapy of cancer using ex vivo expanded human γδ T cells: A new approach

✍ Scribed by Pouneh Dokouhaki; Mei Han; Betty Joe; Ming Li; Michael R. Johnston; Ming-Sound Tsao; Li Zhang


Book ID
116335491
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
957 KB
Volume
297
Category
Article
ISSN
0304-3835

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## Abstract Nitrogen containing‐bisphosphonates (N‐BPs), widely used to treat bone diseases, have direct antitumor effects __via__ the inactivation of Ras proteins. In addition to the direct antitumor activities, N‐BPs expand gdγδT cells, which exhibit major histocompatibility complex‐unrestricted