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NK4, a four-kringle antagonist of HGF, inhibits spreading and invasion of human pancreatic cancer cells

โœ Scribed by Maehara, N; Matsumoto, K; Kuba, K; Mizumoto, K; Tanaka, M; Nakamura, T


Book ID
111724477
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
216 KB
Volume
84
Category
Article
ISSN
0007-0920

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Nk4, a new HGF/SF variant, is an antagon
โœ Christian Parr; Steven Hiscox; Toshikazu Nakamura; Kunio Matsumoto; Wen G. Jiang ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 285 KB ๐Ÿ‘ 1 views

Hepatocyte Growth Factor/Scatter Factor (HGF/SF) is a heterodimeric molecule that plays a key role in the regulation of migration, invasion and angiogenesis in cancer, via activation of its receptor, c-met. HGF/SF is composed of an alpha-chain, containing the N-terminal hairpin domain and 4 kringle