Hepatocyte Growth Factor/Scatter Factor (HGF/SF) is a heterodimeric molecule that plays a key role in the regulation of migration, invasion and angiogenesis in cancer, via activation of its receptor, c-met. HGF/SF is composed of an alpha-chain, containing the N-terminal hairpin domain and 4 kringle
β¦ LIBER β¦
Inhibition of HGF/SF-induced breast cancer cell motility and invasion by the HGF/SF variant, NK4
β Scribed by Stephen Hiscox; Christian Parr; Toshikazu Nakamura; Kunio Matsumoto; Robert E. Mansel; Wen G. Jiang
- Book ID
- 110234501
- Publisher
- Springer US
- Year
- 2000
- Tongue
- English
- Weight
- 131 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0167-6806
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## Abstract Hepatocyte growth factor/scatter factor (HGF/SF) is a multiβfunction cytokine that has been shown to regulate the expression of cell adhesion molecules in human endothelial cells. It is also a key cytokine in the development and progression of cancer, particularly during metastasis. NK4