Nitric oxide production during adjuvant-induced and collagen-induced arthritis
β Scribed by Grant W. Cannon; Scott J. Openshaw; John B. Hibbs Jr.; John R. Hoidal; Thomas P. Huecksteadt; Marie M. Griffiths
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 716 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0004-3591
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Objective. To investigate the role of bone marrow in arthritis. Methods. Bone marrow changes over time were investigated in rats with adjuvant-induced and collageninduced arthritis, using bioassay techniques and histologic analysis. Results. In both animal models, bone marrow interleukin-1 and
It has been previously demonstrated that microglia and astrocytes produce micromolar amounts of nitric oxide in vitro. In this study, we demonstrate that primary rat oligodendrocytes can be stimulated to produce iNOS mRNA as detected by Northern blot and in situ hybridization analysis and a 131-kDa
## Abstract ## Objective To investigate endothelial function and levels of vascular oxidative stress in rat adjuvantβinduced arthritis (AIA), in view of mounting evidence for an association between rheumatoid arthritis (RA) and accelerated vascular disease. ## Methods Thoracic aortic rings were
The role of nitric oxide (NO) from endogenous and exogenous sources in regulating large vessel and microvascular endothelial cell proliferation was investigated. Exogenous NO liberated from five different chemical donors inhibited bovine aortic, bovine retinal microvascular, and human umbilical vein