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Nitric oxide in cystic fibrosis

โœ Scribed by Karin M. de Winter-de Groot; Cornelis K. van der Ent


Book ID
119288424
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
112 KB
Volume
4
Category
Article
ISSN
1569-1993

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โœ Downey, D.; Elborn, J. S. ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 59 KB ๐Ÿ‘ 2 views

Nitric oxide (NO) is produced from three isoforms of nitric oxide synthase (NOS), neuronal (nNOS), endothelial (eNOS) and inducible (iNOS). Cystic ยฎbrosis (CF) patients have an increased bacterial load in the airways which stimulates iNOS and therefore NO production. Upregulation of iNOS in normal e