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Nasal nitric oxide in cystic fibrosis with and without humming

โœ Scribed by V. M. D. Struben; W. V. Sewbalak; M. H. Wieringa; C. J. Mantingh; L. M. Van Den Toorn; M. Bakker; L. Feenstra; J. C. De Jongste

Book ID
108711503
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
171 KB
Volume
37
Category
Article
ISSN
0014-2972

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Nitric oxide (NO) is produced from three isoforms of nitric oxide synthase (NOS), neuronal (nNOS), endothelial (eNOS) and inducible (iNOS). Cystic ยฎbrosis (CF) patients have an increased bacterial load in the airways which stimulates iNOS and therefore NO production. Upregulation of iNOS in normal e