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Nitric oxide and protein nitration in the cystic fibrosis airway

โœ Scribed by Brian M Morrissey; Kevin Schilling; John V Weil; Philip E Silkoff; David M Rodman

Book ID
117042208
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
331 KB
Volume
406
Category
Article
ISSN
0003-9861

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โœ Downey, D.; Elborn, J. S. ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 59 KB ๐Ÿ‘ 2 views

Nitric oxide (NO) is produced from three isoforms of nitric oxide synthase (NOS), neuronal (nNOS), endothelial (eNOS) and inducible (iNOS). Cystic ยฎbrosis (CF) patients have an increased bacterial load in the airways which stimulates iNOS and therefore NO production. Upregulation of iNOS in normal e