Nine Novel Mutations in Maturity-Onset Diabetes of the Young (MODY) Candidate Genes in 22 Spanish Families
✍ Scribed by Barrio, R.; Bellanné-Chantelot, C.; Moreno, J. C.; Morel, V.; Calle, H.; Alonso, M.; Mustieles, C.
- Book ID
- 126951506
- Publisher
- Endocrine Society
- Year
- 2002
- Tongue
- English
- Weight
- 152 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0021-972X
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Maturity onset diabetes of the young (MODY) is a genetically heterogeneous form of type 2 diabetes that is characterized by autosomal dominant inheritance, onset in early adulthood and a primary defect in insulin secretion. Mutations in at least six genes have been shown to underlie MODY, including
Maturity-onset diabetes of the young is a genetically heterogenous autosomal dominant form of diabetes mellitus, characterized by an early age at onset and a primary defect in beta-cell function. Forty families with a clinical presentation suggestive of MODY were screened for the most common MODY su