Maturity onset diabetes of the young (MODY) is a genetically heterogeneous form of type 2 diabetes that is characterized by autosomal dominant inheritance, onset in early adulthood and a primary defect in insulin secretion. Mutations in at least six genes have been shown to underlie MODY, including
Mutations of maturity-onset diabetes of the young (MODY) genes in Thais with early-onset type 2 diabetes mellitus
β Scribed by Nattachet Plengvidhya; Watip Boonyasrisawat; Nalinee Chongjaroen; Prapaporn Jungtrakoon; Sutin Sriussadaporn; Sathit Vannaseang; Napatawn Banchuin; Pa-thai Yenchitsomanus
- Book ID
- 108704270
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 140 KB
- Volume
- 70
- Category
- Article
- ISSN
- 0300-0664
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π SIMILAR VOLUMES
## Maturity -onset diabetes of the young (MODY) resulting from mutations in the glucokinase (GCK) gene accounts for approximately 20% of MODY in the UK. W e have performed fluorescent single stranded conformation polymorphism (F-SSCP) analysis or direct sequencing of the GCK gene in 212 patients re
## Maturity -onset diabetes of the young (MODY) is a clinically heterogeneous group of disorders characterized by early onset non-insulin-dependent diabetes mellitus, autosomal dominant inheritance, and primary defect in the function of the beta cells of the pancreas. Mutations in the glucokinase