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High frequency of mutations in MODY and mitochondrial genes in Scandinavian patients with familial early-onset diabetes

✍ Scribed by M. Lehto; C. Wipemo; S.-A. Ivarsson; C. Lindgren; M. Lipsanen-Nyman; J. Weng; L. Wibell; E. Widén; T. Tuomi; L. Groop


Book ID
105822198
Publisher
Springer
Year
1999
Tongue
English
Weight
108 KB
Volume
42
Category
Article
ISSN
0012-186X

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Maturity onset diabetes of the young (MODY) is a genetically heterogeneous form of type 2 diabetes that is characterized by autosomal dominant inheritance, onset in early adulthood and a primary defect in insulin secretion. Mutations in at least six genes have been shown to underlie MODY, including