Nigellidine — A new indazole alkaloid from the seeds of Nigella sativa
✍ Scribed by Atta-ur-Rahman; Sohail Malik; S.Sadiq Hasan; M.Iqbal Choudhary; Chao-Zhou Ni; Jon Clardy
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 182 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-4039
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## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract The seeds of __Nigella sativa__ Linn contain a new isobenzofuranone derivative, 5‐hydroxy‐2,2‐dimethyl‐2,8‐dihydro‐6__H__‐furo[3,4‐__g__]chromen‐6‐one (1), obtained from the CHCl~3~ extract. Complete ^1^H and ^13^C assignments of the compound were carried out using one‐dimensional stead
The volatile oil of Nigella sativa seeds was prominent in in vitro anti-shigella activity against eight multiple drug resistant strains of Shigella flexneri. The anti-shigella activity against Shigella flexneri Y SH-4 was observed in the sera of monkeys after 45-60 min of oral administration of the