Nicotinic—dopaminergic relationships and radial-arm maze performance in rats
✍ Scribed by Susan R. Mcgurk; Edward D. Levin; Larry L. Butcher
- Book ID
- 119505646
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 574 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0163-1047
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
I n rats, the effects of an intracerebroventricular (ICV) nicotinic agonist nicotine (NIC), the nicotinic antagonist mecamylamine (MEC), and combinations of NIC + MEC were assessed in a radial-arm maze (RAM). In experiment 1, exploratory behavior was assessed in untrained rats (N = 13). The rats rec
Performance on the radial-arm maze depends on the integrity of both cholinergic and dopaminergic systems. We have previously found that administration of either the nicotinic-cholinergic antagonist, mecamylamine, or the muscarinic-cholinergic antagonist, scopolamine, impairs choice accuracy in the r