Chronic nicotine and withdrawal effects on radial-arm maze performance in rats
โ Scribed by Edward D. Levin; Charles Lee; Jed E. Rose; Antonio Reyes; Gaylord Ellison; Murray Jarvik; Ellen Gritz
- Book ID
- 118385056
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 505 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0163-1047
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
I n rats, the effects of an intracerebroventricular (ICV) nicotinic agonist nicotine (NIC), the nicotinic antagonist mecamylamine (MEC), and combinations of NIC + MEC were assessed in a radial-arm maze (RAM). In experiment 1, exploratory behavior was assessed in untrained rats (N = 13). The rats rec
Nicotine and other nicotinic agonists have been found to improve performance in a variety of tasks, including the radial-arm maze to improve memory. There has been an active effort to develop novel nicotinic agonists for the treatment of cognitive dysfunction such as is seen in Alzheimer's disease.