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Nicotine tolerance in rats; role of dose and dose interval

✍ Scribed by I. P. Stolerman; P. Bunker; M. E. Jarvik

Publisher
Springer
Year
1974
Tongue
English
Weight
466 KB
Volume
34
Category
Article
ISSN
0033-3158

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## Abstract A single injection of morphine or isotonic saline was administered to rats at either 1, 5, 9, or 13 days of age. At 26–29 days of age, animals were tested for pain responsivity and activity following either morphine (5 mg/kg) or saline. Animals which received morphine at 1 day of age di