The pharmacokinetics and the dose proportionality of a new anticonvulsant compound, HEPP (D,L-3-hydroxy-3-ethyl-3-phenylpropionamide) was studied in healthy male volunteers as part of the pharmacological evaluation for new drugs. Study was performed administering doses of 250, 375, 500 and 625 mg of
Transdermal delivery of nicotine in normal human volunteers: a single dose and multiple dose study
β Scribed by Y. B. Bannon; J. Corish; O. I. Corrigan; J. G. Devane; M. Kavanagh; S. Mulligan
- Publisher
- Springer
- Year
- 1989
- Tongue
- English
- Weight
- 661 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0031-6970
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Pharmacokinetics of 20 mg isosorbide-5-mononitrate (IS-5-MN) after single and multiple administration of two different tablet formulations were investigated in twelve healthy human subjects using an open, randomized, two-way crossover experimental design. Pentacard@ 20 mg tablets were compared with
The pharmacokinetics of valproic acid (VPA) was investigated in six healthy volunteers. This was done by monitoring total and free (unbound) valproic acid levels in the serum, and the amount of one of its metabolites, VPA glucuronide, in the urine as a function of time, after a single dose administr
The purpose of this study was to examine the pharmacokinetics of three doses of caffeine administered as Stay Alert chewing gum in a multiple dose regimen. ## Methods: A double-blind, parallel randomized, four-treatment study design was employed. the treatment groups were: 50, 100 and 200 mg caffe
## Abstract This was a doubleβblind, randomised, placeboβcontrolled study to investigate the pharmacokinetics and safety of __trans__βresveratrol. In four groups of ten healthy adult subjects (five males and five females), two subjects were randomized to receive placebo and eight subjects to receiv