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Nicotine stimulates the expression of cyclooxygenase-2 mRNA via NFκB activation in human gingival fibroblasts

✍ Scribed by Sumi Nakao; Yorimasa Ogata; Hiroshi Sugiya


Book ID
113466121
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
410 KB
Volume
54
Category
Article
ISSN
0003-9969

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Interleukin-18 stimulates fibronectin ex
✍ Venkatapuram Seenu Reddy; Ralf Egan Harskamp; Margreet Willie van Ginkel; John C 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 430 KB

## Abstract Fibronectin (FN), a key component of the extracellular matrix, is upregulated in cardiac tissue during myocardial hypertrophy and failure. Here we show that interleukin (IL)‐18, a proinflammatory and pro‐hypertrophic cytokine, stimulates FN expression in adult human cardiac fibroblasts