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Nicotine impairs acquisition of radial maze performance in rats

✍ Scribed by William R. Mundy; Edgar T. Iwamoto

Book ID
113222921
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
427 KB
Volume
30
Category
Article
ISSN
0091-3057

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I n rats, the effects of an intracerebroventricular (ICV) nicotinic agonist nicotine (NIC), the nicotinic antagonist mecamylamine (MEC), and combinations of NIC + MEC were assessed in a radial-arm maze (RAM). In experiment 1, exploratory behavior was assessed in untrained rats (N = 13). The rats rec