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Nicotinamide Derivatives as a New Class of Gastric H + /K + -ATPase Inhibitors. 1. Synthesis and Structure−Activity Relationships of N -Substituted 2-(Benzhydryl- and benzylsulfinyl)nicotinamides

✍ Scribed by Terauchi, Hideo; Tanitame, Akihiko; Tada, Keiko; Nakamura, Keiji; Seto, Yasuhiro; Nishikawa, Yoshinori

Book ID
120665246
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
282 KB
Volume
40
Category
Article
ISSN
0022-2623

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ChemInform Abstract: Nicotinamide Deriva
ChemInform Abstract: Nicotinamide Derivatives as a New Class of Gastric H+/K+-ATPase Inhibitors. Part 1. Synthesis and Structure-Activity Relationships of N-Substituted 2-(Benzhydryl- and benzylsulfinyl)nicotinamides.
✍ H. TERAUCHI; A. TANITAME; K. TADA; K. NAKAMURA; Y. SETO; Y. NISHIKAWA 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 35 KB 👁 2 views

Nicotinamide Derivatives as a New Class of Gastric H+/K+-ATPase Inhibitors. Part 1. Synthesis and Structure-Activity Relationships of N-Substituted 2-(Benzhydryl-and benzylsulfinyl)nicotinamides. -A series of title compounds, e.g. (IV), (VIII), (IX), and (X), is synthesized. Acid activation convert