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ChemInform Abstract: Nicotinamide Derivatives as a New Class of Gastric (H+/K+)-ATPase Inhibitors. Part 3. Synthesis and Gastric Antisecretory Activity of 2-( (2- and 4-Aminobenzyl, and α-Methylbenzyl)sulfinyl)-N-(4- pyridinyl)-3-pyridinecarboxamides (I).

✍ Scribed by H. TERAUCHI; A. TANITAME; K. TADA; K. NAKAMURA; Y. SETO; Y. NISHIKAWA


Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
28
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Nicotinamide Deriva
✍ H. TERAUCHI; A. TANITAME; K. TADA; K. NAKAMURA; Y. SETO; Y. NISHIKAWA 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 35 KB 👁 2 views

Nicotinamide Derivatives as a New Class of Gastric H+/K+-ATPase Inhibitors. Part 1. Synthesis and Structure-Activity Relationships of N-Substituted 2-(Benzhydryl-and benzylsulfinyl)nicotinamides. -A series of title compounds, e.g. (IV), (VIII), (IX), and (X), is synthesized. Acid activation convert