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Synthesis and Structure−Activity Relationships of Bafilomycin A 1 Derivatives as Inhibitors of Vacuolar H + -ATPase

✍ Scribed by Gagliardi, Stefania; Gatti, P. Andrea; Belfiore, Pietro; Zocchetti, Andrea; Clarke, Geoffrey D.; Farina, Carlo


Book ID
118154194
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
202 KB
Volume
41
Category
Article
ISSN
0022-2623

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Effects of Bafilomycin A1: An inhibitor
✍ Jiake Xu; Hao Ting Feng; Cathy Wang; Kirk H. M. Yip; Nathan Pavlos; John M. Papa 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 323 KB

## Abstract Bafilomycin A1, a specific inhibitor of V‐ATPases, is a potent inhibitor of bone resorption, but the underlying mechanisms of its action remain unclear. In this study, we investigated the effect of Bafilomycin A1 on endocytosis and apoptosis in RAW cells and RAW cell‐derived osteoclasts