ChemInform Abstract: Chemistry and Structure—Activity Relationships of Bafilomycin A1, a Potent and Selective Inhibitor of the Vacuolar H+-ATPase
✍ Scribed by S. Gagliardi; M. Rees; C. Farina
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 27 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0931-7597
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Nicotinamide Derivatives as a New Class of Gastric H+/K+-ATPase Inhibitors. Part 1. Synthesis and Structure-Activity Relationships of N-Substituted 2-(Benzhydryl-and benzylsulfinyl)nicotinamides. -A series of title compounds, e.g. (IV), (VIII), (IX), and (X), is synthesized. Acid activation convert