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Nickel-Catalyzed Enantio- and Diastereoselective Three-Component Coupling of 1,3-Dienes, Aldehydes, and Silanes Using Chiral N-Heterocyclic Carbenes as Ligands

โœ Scribed by Sato, Yoshihiro; Hinata, Yu; Seki, Reiko; Oonishi, Yoshihiro; Saito, Nozomi


Book ID
127382453
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
88 KB
Volume
9
Category
Article
ISSN
1523-7060

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Nickel(0)-catalyzed diastereoselective t
โœ Nozomi Saito; Tetsuro Yamazaki; Yoshihiro Sato ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 211 KB

A nickel-catalyzed diastereoselective alkylative three-component coupling of 1,3-diene and aldehyde with organoboron or organosilicon reagents has been realized. The diastereoselectivity was dramatically changed depending on the class of organometallic reagents. The reaction using ArB(OH) 2 in the p