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ChemInform Abstract: Nickel-Catalyzed Enantio- and Diastereoselective Three-Component Coupling of 1,3-Dienes, Aldehydes, and a Silylborane Leading to α-Chiral Allylsilanes.

✍ Scribed by Nozomi Saito; Ayami Kobayashi; Yoshihiro Sato


Book ID
112045454
Publisher
John Wiley and Sons
Year
2012
Weight
46 KB
Volume
43
Category
Article
ISSN
0931-7597

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Nickel(0)-catalyzed diastereoselective t
✍ Nozomi Saito; Tetsuro Yamazaki; Yoshihiro Sato 📂 Article 📅 2008 🏛 Elsevier Science 🌐 French ⚖ 211 KB

A nickel-catalyzed diastereoselective alkylative three-component coupling of 1,3-diene and aldehyde with organoboron or organosilicon reagents has been realized. The diastereoselectivity was dramatically changed depending on the class of organometallic reagents. The reaction using ArB(OH) 2 in the p