A mild, efficient method for the oxidati
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Puhui Li; Max M. Majireck; Ilia Korboukh; Steven M. Weinreb
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Article
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2008
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Elsevier Science
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French
⚖ 113 KB
A wide variety of alpha-diazo-beta-ketoesters can be prepared in good overall yields via a two-step sequence involving addition of ethyl lithiodiazoacetate to aliphatic, aromatic and conjugated aldehydes followed by mild oxidation with the Dess-Martin periodinane.