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A mild, efficient method for the oxidation of α-diazo-β-hydroxyesters to α-diazo-β-ketoesters

✍ Scribed by Puhui Li; Max M. Majireck; Ilia Korboukh; Steven M. Weinreb

Publisher
Elsevier Science
Year
2008
Tongue
French
Weight
113 KB
Volume
49
Category
Article
ISSN
0040-4039

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✦ Synopsis

A wide variety of alpha-diazo-beta-ketoesters can be prepared in good overall yields via a two-step sequence involving addition of ethyl lithiodiazoacetate to aliphatic, aromatic and conjugated aldehydes followed by mild oxidation with the Dess-Martin periodinane.

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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.