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Tetrabutylammonium fluoride-promoted α-[11C]methylation of α-arylesters: a simple and robust method for the preparation of 11C-labeled ibuprofen

✍ Scribed by Koichi Kato; Tatsuya Kikuchi; Nobuki Nengaki; Takuya Arai; Ming-Rong Zhang


Publisher
Elsevier Science
Year
2010
Tongue
French
Weight
315 KB
Volume
51
Category
Article
ISSN
0040-4039

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✦ Synopsis


Tetrabutylammonium fluoride-promoted a-[ 11 C]methylation of a-arlylesters was developed. The method was amenable to the remote-controlled synthesis of 11 C-labeled ibuprofen.


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