Next Generation Sequencing and Sequence Assembly: Methodologies and Algorithms

✍ Scribed by Ali Masoudi-Nejad, Zahra Narimani, Nazanin Hosseinkhan (auth.)

• Publisher: Springer-Verlag New York
• Year: 2013
• Tongue: English
• Leaves: 92
• Series: SpringerBriefs in Systems Biology 4
• Edition: 1
• Category: Library

✦ Synopsis

The goal of this book is to introduce the biological and technical aspects of next generation sequencing methods, as well as algorithms to assemble these sequences into whole genomes. The book is organized into two parts; part 1 introduces NGS methods and part 2 reviews assembly algorithms and gives a good insight to these methods for readers new to the field. Gathering information, about sequencing and assembly methods together, helps both biologists and computer scientists to get a clear idea about the field. Chapters will include information about new sequencing technologies such as ChIp-seq, ChIp-chip, and De Novo sequence assembly. ​

✦ Table of Contents

Front Matter....Pages i-x
Next-Generation Sequencing Methodologies....Pages 1-9
Emergence of Next-Generation Sequencing....Pages 11-39
The Assembly of Sequencing Data....Pages 41-54
De Novo Assembly Algorithms....Pages 55-83
Back Matter....Pages 85-86

✦ Subjects

Human Genetics; Systems Biology; Biomedicine general