Advances in sequencing technology have allowed scientists to study the human genome in greater depth and on a larger scale than ever before โ as many as hundreds of millions of short reads in the course of a few days. But what are the best ways to deal with this flood of data? Algorithms for Next
Algorithms for next-generation sequencing
โ Scribed by Sung, Wing-Kin
- Publisher
- Chapman and Hall/CRC
- Year
- 2017
- Tongue
- English
- Leaves
- 364
- Series
- Chapman & Hall/CRC mathematical and computational biology series
- Edition
- 1
- Category
- Library
No coin nor oath required. For personal study only.
โฆ Table of Contents
Content: Cover
Half Title
Title Page
Copyright Page
Table of Contents
Preface
1: Introduction
1.1 DNA, RNA, protein and cells
1.2 Sequencing technologies
1.3 First-generation sequencing 1.4 Second-generation sequencing 1.4.1 Template preparation
1.4.2 Base calling 1.4.3 Polymerase-mediated methods based on reversible terminator nucleotides 1.4.4 Polymerase-mediated methods based on unmodied nucleotides
1.4.5 Ligase-mediated method 1.5 Third-generation sequencing 1.5.1 Single-molecule real-time sequencing
1.5.2 Nanopore sequencing method 1.5.3 Direct imaging of DNA using electron microscopy 1.6 Comparison of the three generations of sequencing
1.7 Applications of sequencing
โฆ Subjects
General
๐ SIMILAR VOLUMES
<p>The goal of this book is to introduce the biological and technical aspects of next generation sequencing methods, as well as algorithms to assemble these sequences into whole genomes. The book is organized into two parts; part 1 introduces NGS methods and part 2 reviews assembly algorithms and gi