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New synthesis of 8-chloro-1-[2-(dimethylamino)ethyl]-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine, which has antidepressant properties

✍ Scribed by Hester, Jackson B.

Book ID
127317013
Publisher
American Chemical Society
Year
1979
Tongue
English
Weight
618 KB
Volume
44
Category
Article
ISSN
0022-3263

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📜 SIMILAR VOLUMES

Synthesis of carbon-14 labeled 1,4-benzo
Synthesis of carbon-14 labeled 1,4-benzodiazepines. IV. Carbon-13 and carbon-14 labeled 8-chloro-1-(2-dimethylamino)ethyl-6-phenyl-4H-s-triazolo[4,3-a][1,4]-benzodiazepine tosylate
✍ Richard S. P. Hsi; Wayne T. Stolle 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 French ⚖ 341 KB

## Abstract Carbon‐13 and carbon‐14 labeled forms of the title compound have been prepared from the correspondingly labeled forms of 8‐chloro‐1‐methyl‐6‐phenyl‐4H‐__s__‐triazolo[4,3‐a][1,4]benzodiazepine (__3__)Alprazolam is the generic USAN name for this compound. . A modified and more convenient

Synthesis of carbon-14 labeled 1,4-benzo
Synthesis of carbon-14 labeled 1,4-benzodiazepines. III. 2-allyloxy-amino-7-chloro-5-(2-chlorophenyl)-3h-l,4-benzodiazepine-2-14C, 8-chloro-1-dimethylamino-methyl-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine-3a-14C, and 8-chloro-2,4-dihydro-2-methyl-6-phenyl-1H-s-triazolo[4,3-a] [1,4]benzodiazepin-l-one-3a-14
✍ Richard S. P. Hsi; Tommy D. Johnson 📂 Article 📅 1976 🏛 John Wiley and Sons 🌐 French ⚖ 281 KB 👁 1 views

## Abstract A group of radioactive 1,4‐benzodiazepine derivatives have been synthesized from glycine‐1‐^14^C. The subject compounds are labeled with carbon‐14 in the 2‐position of the 1,4‐benzodiazepine ring system.

Synthesis of 8-chloro-6-phenyl-4H-s-tria
Synthesis of 8-chloro-6-phenyl-4H-s-triazolo [4,3-a] [1,4] benzo-diazepine-1-14C
✍ Nobuyoshi Hayashi; Kazuo Shinozaki; Shinji Kato; Kanji Meguro; Yutaka Kuwada 📂 Article 📅 1974 🏛 John Wiley and Sons 🌐 French ⚖ 155 KB 👁 1 views

## Abstract 8‐Chloro‐6‐phenyl‐4H‐s‐triazolo [4,3‐a] [1,4] benzodiazepine (D‐40TA)‐1‐^14^C (V‐^14^C) was synthesized by the reaction of formic acid‐^14^C with 7‐chloro‐2‐hydrazino‐5‐phenyl‐3H‐1, 4‐benzodiazepine in the presence of N,N′‐carbonylbis (2‐methylimidazole). The overall radio‐chemical yiel