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New Set of Orthogonal Protecting Groups for the Modular Synthesis of Heparan Sulfate Fragments

✍ Scribed by Prabhu, Arati; Venot, Andre; Boons, Geert-Jan

Book ID
127145608
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
90 KB
Volume
5
Category
Article
ISSN
1523-7060

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The first synthesis of N-Boc-protected tropanes by a [4+3] cycloaddition reaction is described. The Boc group has been cleanly removed demonstrating that this group would be very useful for the synthesis of 'tropane-like' scaffolds for combinatorial chemistry.