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tert-Butoxycarbamate group: a useful protecting group for the synthesis of orthogonally protected ‘tropane-like’ scaffolds

✍ Scribed by Jean-Laurent Paparin; Christophe Crévisy; René Grée

Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
131 KB
Volume
41
Category
Article
ISSN
0040-4039

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✦ Synopsis

The first synthesis of N-Boc-protected tropanes by a [4+3] cycloaddition reaction is described. The Boc group has been cleanly removed demonstrating that this group would be very useful for the synthesis of 'tropane-like' scaffolds for combinatorial chemistry.

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