Synthesis of 5-[(4-phenylpiperazin-1-yl)
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Sabine Linz; Reinhard Troschütz
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Article
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2007
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Journal of Heterocyclic Chemistry
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English
⚖ 426 KB
## Abstract magnified image A series of pyrrolo[2,3‐__d__]pyrimidine Mannich bases of type **9, 12, 15** and **16** have been prepared as potential dopamine D4 receptor ligands. The syntheses start from 4‐aminopyrimidin‐6‐one **3** with pyrrole annulations and Mannich reactions with formaldehyde a