N-(4-(4-(2-Halogenophenyl)piperazin-1-yl)butyl) Substituted Cinnamoyl Amide Derivatives as Dopamine D2 and D3 Receptor Ligands.

N-(4-(4-(2-Halogenophenyl)piperazin-1-yl

N-(4-(4-(2-Halogenophenyl)piperazin-1-yl)butyl) Substituted Cinnamoyl Amide Derivatives as Dopamine D2 and D3 Receptor Ligands

✍ Oliver Saur; Anneke E. Hackling; Sylvie Perachon; Jean-Charles Schwartz; Pierre 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 342 KB 👁 1 views

Synthesis of 5-[(4-phenylpiperazin-1-yl)

Synthesis of 5-[(4-phenylpiperazin-1-yl)methyl]pyrrolo-[2,3-d]pyrimidine derivatives as potential dopamine D4 receptor ligands

✍ Sabine Linz; Reinhard Troschütz 📂 Article 📅 2007 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 426 KB

## Abstract magnified image A series of pyrrolo[2,3‐__d__]pyrimidine Mannich bases of type **9, 12, 15** and **16** have been prepared as potential dopamine D4 receptor ligands. The syntheses start from 4‐aminopyrimidin‐6‐one **3** with pyrrole annulations and Mannich reactions with formaldehyde a

Synthesis and radiolabelling of [123I]-4

Synthesis and radiolabelling of [123I]-4-iodo-N-(4-(4-(2-methoxyphenyl)-piperazin-1-yl)butyl)-benzamide, a potential dopamine D3 antagonist for SPECT studies

✍ L. Staelens; F. Dumont; F. De Vos; R. Oltenfreiter; M. Vandecapelle; R.A. Dierck 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 French ⚖ 95 KB 👁 1 views

## Abstract Schizophrenia is a devastating mental disorder characterized by relapsing psychotic episodes accompanied with emotional, professional and social decline. The classical dopamine hypothesis of schizophrenia postulates that hyperactivity of dopaminergic neurotransmission is responsible for

Synthesis and radiolabelling of [123I]-4

Synthesis and radiolabelling of [123I]-4-iodo-N-(4-(4-(2-methoxyphenyl)-piperazin-1-yl)butyl)-benzamide, a potential dopamine D3 antagonist for SPECT studies

✍ L. Staelens; F. Dumont; F. De Vos; R. Oltenfreiter; M. Vandecapelle; R. A. Dierc 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 French ⚖ 98 KB 👁 1 views

## Abstract Schizophrenia is a devastating mental disorder characterized by relapsing psychotic episodes accompanied with emotional, professional and social decline. The classical dopamine hypothesis of schizophrenia postulates that hyperactivity of dopaminergic neurotransmission is responsible for

Development of Novel 1,2,3,4-Tetrahydroi

Development of Novel 1,2,3,4-Tetrahydroisoquinoline Derivatives and Closely Related Compounds as Potent and Selective Dopamine D3 Receptor Ligands

✍ Ulrich R. Mach; Anneke E. Hackling; Sylvie Perachon; Sandrine Ferry; Camille G. 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 226 KB 👁 1 views

ChemInform Abstract: Functional Characte

ChemInform Abstract: Functional Characteristics of a Series of N4-Substituted 1-(2,3-Dihydro-1,4-benzodioxin-5-yl)piperazines as 5-HT1A Receptor Ligands. Structure—Activity Relationships.

✍ B. J. VAN STEEN; I. VAN WIJNGAARDEN; E. RONKEN; W. SOUDIJN 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 34 KB 👁 2 views