Starting from N-pivaloyl-Uhle's ketone a new synthetic approach to the ergoline skeleton has been elaborated. Ring D of the tetracyclic skeleton was formed by an intramolecular Dieckmann-condensation of a diester, obtained in a Reformatsky reaction of a properly substituted derivative of N-pivaloyl
โฆ LIBER โฆ
New Route to the Ergoline Skeleton via Cyclization of 4-Unsubstituted Indoles
โ Scribed by Burley, Scott D.; Lam, Vicky V.; Lakner, Frederick J.; Bergdahl, B. Mikael; Parker, Matthew A.
- Book ID
- 120340822
- Publisher
- American Chemical Society
- Year
- 2013
- Tongue
- English
- Weight
- 283 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1523-7060
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